Belize Medical And Dental Association

Most prostate cancer is now detected at a localized stage, presumably because of screening for prostate-specific antigen (PSA), and the 5-year survival rate for patients with local disease is nearly 100%. Some experts are now concerned about overdiagnosis and overly aggressive treatment, yet others argue for lowering the PSA threshold for biopsy even further.

Researchers describe 180 isolates from patients in India, Pakistan, the U.K., and other countries. The isolates produce an enzyme, New Delhi  metallo-beta-lactamase 1 (NDM-1) whose gene can be carried both on bacterial chromosomes and plasmids. NDM-1 was identified in up to 44% of carbapenem-resistant isolates in U.K. patients, some of whom had undergone elective surgical procedures in India or Pakistan.

The risk for sudden cardiac death (SCD) is particularly high in the early months after a myocardial infarction (MI). However, two trials of prophylactic implantable cardioverter-defibrillator (ICD) placement after MI failed to show a survival benefit in ICD recipients, in contrast to results of other ICD trials. To examine this lack of benefit more closely, investigators studied data from  VALIANT, an international trial of valsartan in MI survivors.

Chronic drooling in children and youth with neurological disorders can be a disabling symptom that affects swallowing and hygiene. It is often seen in patients with cerebral palsy and other neuromuscular and developmental conditions that adversely affect oropharyngeal muscle coordination and the elimination of oral secretions through effective swallowing.