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Syncope due to ictal asystole PDF Print E-mail
Posted by Dr. Johanne Perez M.D   
Monday, 14 July 2008 00:00
Syncope due to ictal asystole..Met Synd Thrombolysis in MCA Ischemic Stroke


News ImageAlthough most seizures are associated with sinus tachycardia, a minority are associated with bradycardia and even asystole (which is usually defined as a sinus pause lasting at least 3 seconds).

An increasing number of case reports and series have focused on this phenomenon in recent years. Now, researchers report on three patients with sudden falls that were found to be due to seizure-induced asystole and syncope.

In each case, simultaneous EEG and electrocardiogram recordings identified the cause of the falls. The cases, supplemented by video clips on the Neurology website, provide convincing demonstrations of falls associated with seizure-induced asystole.

Comment: As is noted in an editorial, sudden falls are potentially dangerous in themselves. Even though a connection has not been established between ictal bradycardia or asystole and the phenomenon of sudden unexpected death in epilepsy, patients with seizure-induced cardiac asystole probably should be treated not only with the best available antiepileptic therapy, but also with cardiac pacing. The report also highlights the complex interactions between cerebral and cardiovascular dysfunctions that contribute to episodic unconsciousness. Clinicians must keep in mind that the spectrum of episodic unconsciousness includes not only ictal asystole but also the more common phenomenon of convulsive syncope (convulsive movements due to cerebral hypoperfusion without an epileptic discharge) and very rare cases of hypoperfusion-induced acute symptomatic seizures.

— Edward B. Bromfield, MD

Dr. Bromfield is Chief, Division of Epilepsy and Sleep Neurology, Brigham and Women’s Hospital, Boston.

Published in Journal Watch Neurology July 15, 2008

Citation(s):

Rubboli G et al. Sudden falls due to seizure-induced cardiac asystole in drug-resistant focal epilepsy. Neurology 2008 May 13; 70:1933.

Krumholz A and Hopp J. Falls give another reason for taking seizures to heart. Neurology 2008 May 13; 70:1874.
Last Updated on Thursday, 31 July 2008 19:48